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Thirdly, patients with Down syndrome or autism have increased oxidative stress and exhibit particular disturbed profiles of one-carbon metabolism [1315]

Longitudinal registration was processed with Inscopix software and a custom MATLAB script to track the same neurons across sessions as described 71,72 ( Quantification and statistical analysis OriginPro 2017 software (OriginLab Corporation, USA) and GraphPad Prism 8 (GraphPad Software, Inc., USA) were used for the statistical analyses and graphing

Most patients experience appetite suppression within 12 weeks and measurable weight loss within 48 weeks

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Evidence and Procedure Any classification change request must be supported by strong evidence that demonstrates the risk to the public will be adequately managed